矽肺的发生发展是受多种因素影响的复杂的病理变化过程。矽肺发病原理的研究已有几十年的历史,但至今尚未完全认识和解决。为解释该问题,先后提出了多种的观点和学说,其中主要的有:机械刺激、化学毒性、矽酸聚合、压电效应、放射性能和免疫学说等。以上各学说虽为矽肺的诊断、治疗提出了很多方法和途径,但用辩证唯物主义的观点分析,普遍存在两种倾向:1)偏重于致病因子(矽尘)对机体的危害,忽略了机 The development of silicosis is a complex pathological process influenced by many factors. The pathogenesis of silicosis has been decades of history, but so far not yet fully understand and solve. In order to explain this problem, a variety of opinions and theories have been put forward. The main ones are mechanical stimulation, chemical toxicity, silicic acid polymerization, piezoelectric effect, radioactivity and immune theory. Although the above theories put forward many methods and approaches for the diagnosis and treatment of silicosis, there are two common tendencies in dialectical materialism: 1) the emphasis on the risk of the pathogenic factor (silica dust) on the body is neglected machine