发音钮是全喉切除术后病人发音重建的常用方法之一。但其最大的缺点是植入数周后 ,霉菌及细菌粘附于发音钮表面形成了生物膜 ,增加了通气阻力 ,损坏了发音钮的功能。因此 ,发音钮通常 3～ 4个月需要更换一次。经分析发音钮表面生物膜上的主要菌落为 :念珠菌为主的霉菌 ,链球菌 The articulation button is one of the commonly used methods for reconstructing the patient’s voice after total laryngectomy. However, its biggest drawback is that after a few weeks of implantation, molds and bacteria adhere to the surface of the knob to form a biofilm, which increases ventilation resistance and damages the function of the knob. Therefore, the pronunciation button usually 3 to 4 months need to be replaced once. The main knobs on the surface biofilms were analyzed by the analysis knobs: Candida-dominant molds, Streptococcus