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目的:探讨动态脑电图(AEEG)监测在指导抗癫药物治疗中的作用。方法:对45例癫病例进行122次AEEG随访监测,每例每次均作30min常规脑电图(REEG)描记,以作自身对照。结果:REEG描记45例中,首次监测正常41例(91%),异常4例(9%),其中有样放电1例。AEEG首次监测正常8例(18%),异常37例(82%),其中有样放电33例,占异常的89%。AEEG与REEG阳性率及样波检出率经统计学处理,分别为χ2=48.79,P<0.001及χ2=10.51,P<0.01,差异均有非常显著性意义。结论:AEEG阳性率及样放电检出率均明显高于REEG。如果仅用REEG结果指导抗癫药物的应用,就可能会使那些尚需继续用药的患者将药物停掉,依据AEEG对抗癫药物的选用,比依据REEG更有价值。
Objective: To investigate the role of dynamic electroencephalogram (AEEG) monitoring in guiding anti-epileptic drug treatment. Methods: A total of 122 cases of epilepsy were enrolled in this study. 122 cases of epilepsy were followed up for surveillance. Each case was performed 30-minute conventional electroencephalography (REEG). Results: In the 45 cases of REEG, 41 cases (91%) were normal and 4 cases (9%) were abnormal. Among them, there were 1 cases of abnormal discharge. AEEG first monitored normal in 8 cases (18%) and abnormal in 37 cases (82%), of which 33 cases were abnormal discharge, accounting for 89% of abnormal. The positive rate of AEEG and REEG and the detection rate of -like wave were statistically analyzed, which were χ2 = 48.79, P <0.001 and χ2 = 10.51 respectively, P <0.01. The differences were statistically significant. Conclusion: The positive rate of AEEG and the positive rate of like discharge were significantly higher than that of REEG. Using REEG alone to guide the use of antiepileptic drugs may result in discontinuation of medication in those patients who are still on medication, and the use of epileptic drugs based on AEEG is more valuable than REEG.