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目的:探讨孕前体重指数与妊娠期糖代谢异常发病及其临床特点的关系。方法:采用病例-对照研究的方法,对孕期在我院进行健康保健确诊为糖代谢异常并已完成分娩的孕妇130例作为病例组,同时随机抽取同期分娩的260例糖代谢正常孕妇作为对照组。用Logistic回归模型对孕前体重指数进行单因素分析;计算其相对危险度。结果:病例组孕妇孕前BMI指数大于25者占80.77%,明显高于对照组的(19.23%),差别有统计学意义(X2=30.469,P<0.05)。logistic回归结果显示相对于BMI小于25者,BMI>25组发生糖代谢异常的相对危险度是3.90,95%CI为2.23-6.41。结论:孕妇孕前体重指数是妊娠期糖代谢异常的独立危险因素,因此孕前控制体重指数是降低孕期糖代谢异常发生的关键因素。
Objective: To investigate the relationship between pre-pregnancy body mass index and abnormal glucose metabolism during pregnancy and its clinical features. Methods: A case-control study of pregnant women in our hospital for health care diagnosed during pregnancy as abnormal glucose metabolism and have completed delivery of pregnant women as a case group of 130 cases at the same time randomly selected 260 cases of normal glucose metabolism in pregnant women as a control group . Logistic regression model was used to univariate analysis the body mass index before pregnancy; the relative risk was calculated. Results: The BMI index of pregnant women before pregnancy was more than 25 (80.77%), significantly higher than that of the control group (19.23%), the difference was statistically significant (X2 = 30.469, P <0.05). Logistic regression analysis showed that relative risk of abnormal glucose metabolism was 3.90 and 95% CI was 2.23-6.41 in BMI> 25 relative to those with BMI <25. Conclusion: The body mass index of pregnant women before pregnancy is an independent risk factor of abnormal glucose metabolism during pregnancy. Therefore, controlling body mass index before pregnancy is the key factor to reduce the occurrence of abnormal glucose metabolism during pregnancy.