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我们于1983年开始选择活血化瘀类中药川芎嗪、丹参及西药肝素、酚妥拉明等,分别进行对肺动脉压影响的动物实验研究。现先将活血化瘀中药对肺动脉影响的实验研究部分小结于下。实验方法一、实验动物的准备实验家犬体重为10～50公斤,按25～30毫克/公斤体重用戊巴比妥纳进行腹腔麻醉后,接上心电图机描记心电波型及心电示波器监测心律;分离出左颈外静脉,插入微型心导管(内径1毫米的漂浮导管),插管过程中不时注入0.05％肝素抗凝,直至进入肺
In 1983, we began to select experimental animals with traditional Chinese medicines such as ligustrazine, salvia miltiorrhiza, heparin, and phentolamine, which were used to treat pulmonary arterial pressure. The experimental study of the effects of traditional Chinese medicines for promoting blood circulation and phlegm on pulmonary arteries is first summarized below. Experimental Method I. Preparation of Experimental Animals The experimental dog has a body weight of 10 to 50 kilograms. After abdominal anesthesia is performed at a dose of 25 to 30 mg/kg body weight using pentobarbital, the electrocardiogram is traced and the electrocardiographic monitoring is performed. Heart rhythm; the left external jugular vein was isolated and a miniature cardiac catheter (a floating catheter with an internal diameter of 1 mm) was inserted. From time to time, 0.05% heparin anticoagulation was injected during the intubation until it entered the lungs.