能够选择性地阻滞β-肾上腺素能受体的药物出现,是近三十年来人体药理学中最有成效和治疗学上最令人鼓舞的进展之一。这些药物对于加深理解实验动物和人体(特别是在人体)中许多功能的生理性调节机理具有极大的价值。虽然,β-肾上腺素能受体阻滞药(以下简称β-阻滞药)最初是作为一种治疗心绞痛的药物,但很快发现它在其他一些临床情况 The ability to selectively block the emergence of β-adrenergic receptors has been one of the most productive and therapeutically most encouraging advances in human pharmacology in the last three decades. These drugs are of tremendous value in understanding the physiological regulation of many functions in laboratory animals and in humans, especially in humans. Although β-adrenergic blockers (hereinafter referred to as β-blockers) were originally used as a medicine for the treatment of angina, it was soon found that in other clinical situations