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目的 :探讨急性毒鼠强中毒是心肌酶学及心肌钙蛋白T的变化及原因。方法 :测定 5 1例急性毒鼠强中毒患者血清心肌酶谱值 (CK、CK -MB、AST、LDH、α -HBDH )及心肌钙蛋白T ,同时以健康人及急性心肌梗死患者作为对照。结果 :中毒组患者血清心肌酶谱值均有不同程度升高 ,CK、CK -MB、LDH升高较为明显 ,而AST、α -HBDH升高不明显 ;而且心肌钙蛋白T阳性率中毒组明显低于心梗组。结论 :急性毒鼠强中毒患者血清心肌酶谱值升高可能为骨骼肌损伤所致 ,而非心脏损害
Objective: To investigate the changes of cardiac enzymes and cardiac troponin T in acute tetramine poisoning and its causes. Methods: The serum levels of myocardial enzymes (CK, CK-MB, AST, LDH, α -HBDH) and cardiac troponin T in 51 acute tetramine poisoning patients were determined and compared with healthy people and acute myocardial infarction patients. Results: The values of serum myocardial enzymes in patients of poisoning group were increased to some extent, the levels of CK, CK-MB and LDH were obviously increased, while the levels of AST and α-HBDH were not significantly increased; and the positive rate of cardiac troponin T was significantly higher Lower than myocardial infarction group. Conclusion: The increase of serum myocardial enzymes in patients with acute tetramine poisoning may be caused by skeletal muscle injury rather than heart damage