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目的 通过多种磁共振血管造影 (MRA)技术对模拟狭窄血管的体外模型和四肢血管性疾病应用研究分析 ,评估其临床应用价值和限度。材料与方法 ( 1)实验研究 :对不同狭窄程度、长度的模型行二维时间飞跃法磁共振血管造影 ( 2DTOFMRA)、幅度对比血管造影 (MCA)、增强幅度对比血管造影 (CEMCA)和三维动态增强磁共振血管造影 ( 3DCEMRA)检查 ,测量并计算狭窄程度、长度和分级准确度。 ( 2 )临床应用 :对 2 0例怀疑有四肢血管相关性疾病的患者行 3DCEMRA、2DTOFMRA和幅度对比MRA (MCMRA)。比较其图像质量和血管显示情况。结果 ( 1)实验研究 :2DTOFMRA、MCA、CEMCA和 3DCEMRA对明显狭窄 ( 69% )的分级准确度分别为 3 6.4%、9.1%、18.2 %和 72 .7% ,3DCEMRA对明显狭窄 (≥ 5 0 % )的评估优于其他MRA方法 (P <0 .0 0 1) ,但比起真实值仍有明显高估 (P <0 .0 0 1)。( 2 )临床应用 :2DTOFMRA、MCA和 3DCEMRA的动脉显示率分别为 92 .6%、94.4%和 98.1% ,以及对 12例血管瘤的异常血管显示分别为 0例、6例和 11例。 3DCEMRA均能较好地显示血管狭窄程度、供血血管起源、病变部位及病灶与血管的关系。结论 3DCEMRA无论是图像质量、狭窄程度的评估还是病灶的供血血管及病灶与血管关系的显示具有明显优势 ,但对狭窄程
Objective To evaluate and evaluate the clinical value and limitations of in vitro models and extremities vascular diseases by using multiple magnetic resonance angiography (MRA). Materials and Methods (1) Experimental study: 2DTOFMRA, MCA, CEMCA and 3D dynamic imaging were performed on the patients with different degree of stenosis and length underwent two-dimensional time-of-flight magnetic resonance angiography Enhanced magnetic resonance angiography (3DCEMRA) examination, measurement and calculation of stenosis, length and grading accuracy. (2) Clinical application: 3DCEMRA, 2DTOFMRA and amplitude contrast MRA (MCMRA) were performed in 20 patients with suspected vascular diseases. Compare the image quality and vascular display. Results (1) Experimental study: The classification accuracy of 2DTOFMRA, MCA, CEMCA and 3DCEMRA for obvious stenosis (69%) were 3 6.4%, 9.1%, 18.2% and 72.7% %) Was superior to other MRA methods (P <0. 001), but it was still significantly overestimated compared with the true value (P <0.001). (2) Clinical application: The arterial display rates of 2DTOFMRA, MCA and 3DCEMRA were 92.6%, 94.4% and 98.1% respectively, and the abnormal vessels in 12 hemangiomas were 0, 6 and 11, respectively. 3DCEMRA can better show the degree of vascular stenosis, the origin of blood vessels, lesions and lesions and vascular relationship. Conclusions 3DCEMRA has obvious advantages both in terms of image quality, assessment of stenosis, blood vessel of lesion and the relationship between lesion and blood vessel. However,