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目的探讨对瘢痕子宫孕妇引产操作中给予依沙吖啶羊膜腔内注射配伍口服米非司酮的临床效果。方法将2009年10月至2012年8月间在县计划生育服务站住院的57例瘢痕子宫引产患者随机分为两组:独立组和配伍组。独立组仅给予依沙吖啶羊膜腔内注射,配伍组给予依沙吖啶羊膜腔内注射配伍口服米非司酮,对比产程耗时、引产各阶段耗时以及产后情况。结果配伍组的产程耗时、引产各阶段耗时均低于独立组,差异有统计学意义(P<0.01);配伍组的引产效果优于独立组,差异有统计学意义(P<0.05);配伍组的的出血量更少、残留率更小,配伍组的产后情况优于独立组,差异有统计学意义(P<0.01),软产道破损比例降低,差异无统计学意义(P>0.05)。结论在瘢痕子宫引产操作中给予依沙吖啶羊膜腔内注射配伍口服米非司酮能够降低产程耗时,提高引产效果,避免出现产后并发症。
Objective To investigate the clinical effect of intramuscular injection of ethambutol combined with oral administration of mifepristone during the induction of labor in pregnant women with scarring uterus. Methods Fifty-seven patients with induced uterine scar from October 2009 to August 2012 in county family planning service station were randomly divided into two groups: independent group and compatibility group. In the independent group, amniotic fluid was injected into the amniotic cavity only, and the compatibility group was given intramuscular injections of amoxicillin combined with oral mifepristone. The time course of labor was compared with that of the labor group. Results Compared with the independent group, the time-consuming and labor-inducing in the compatibility group were shorter than those in the independent group (P <0.01), the induction effect in the compatibility group was better than that in the independent group (P <0.05) ; The compatibility group had less bleeding and the residual rate was smaller. The postpartum condition in the compatibility group was better than that in the independent group (P <0.01), and the percentage of soft birth canal damage was not significant (P> 0.05). Conclusion In the operation of scarring uterine induction of amniotic fluid administration of amniotic fluid in combination with oral administration of mifepristone can reduce the labor-induced labor, improve the effect of induction of labor, to avoid postpartum complications.