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目的分析2型糖尿病患者血糖波动幅度和血超敏C反应蛋白(hs-CRP)的关系。方法以224例2型糖尿病住院患者为研究对象,根据血糖水平的标准差(SDBG)范围不同分1～3组,1组为SDBG<1.4mmol/L患者,2组为1.4mmol/L≤SDBG≤2.5mmol/L患者,3组为SDBG>2.5mmol/L患者,观察各组间hs-CRP的变化。结果 2组及3组患者hs-CRP较1组患者明显增高(P<0.05),且hs-CRP在2组及3组间差异也具有统计学意义(P<0.05)。结论糖尿病患者的血糖波动幅度与hs-CRP密切相关。
Objective To analyze the relationship between blood glucose fluctuation and serum hs-CRP in type 2 diabetic patients. Methods A total of 224 inpatients with type 2 diabetes mellitus were enrolled in this study. SDBG ranged from 1 to 3, with SDBG <1.4 mmol / L in group 1 and 1.4 mmol / L≤SDBG ≤ 2.5mmol / L patients, three groups were SDBG> 2.5mmol / L patients, observed the changes of hs-CRP among the groups. Results The hs-CRP levels in group 2 and group 3 were significantly higher than those in group 1 (P <0.05), and the difference of hs-CRP between groups 2 and 3 was also statistically significant (P <0.05). Conclusion The fluctuation of blood glucose in diabetic patients is closely related to hs-CRP.