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口腔颌面部恶性肿瘤约占全身恶性肿瘤3%,90%为鳞状细胞癌,其中口腔鳞癌(oral squamous cell carcinoma,OSCC)最常见。OSCC是人类第六大恶性肿瘤,全球范围内OSCC占所有新发癌症病例的4%~7%,是影响人群健康的重要疾病,严重威胁人们的生活和健康~([1])。虽然近几十年来对OSCC的治疗取得了巨大的发展,但目前经治疗后OSCC的5年生存率也仅为50%~60%~([2])。OSCC常由口腔黏膜
Oral and maxillofacial malignancies account for about 3% of all malignant tumors and 90% are squamous cell carcinomas, of which oral squamous cell carcinoma (OSCC) is the most common. OSCC is the sixth largest human malignant tumor in the world. OSCC accounts for 4% -7% of all newly-developed cancer cases in the world. OSCC is an important disease affecting people’s health and seriously threatening people’s life and health ([1]). Although the treatment of OSCC has made tremendous progress in recent decades, the 5-year survival rate of OSCC after treatment is only 50% -60% ~ ([2]). OSCC often by the oral mucosa