T细胞杂交是近年来发展起来的一项新技术,它是继B细胞杂交后细胞融合技术在免疫学研究中的又一成功应用。众所周知,正常的T细胞难于在体外长期生长;而T淋巴瘤细胞则可在体外条件下无限地增殖。将这两种细胞融合后,我们所期望获得的,分别来自于两个亲代细胞的性状均可由T杂交瘤子代细胞所表现出来,T杂交瘤既具有亲代正常T细胞执行免疫功能的能力,又具有亲代瘤细胞在体外培养中或作为移植瘤在动物体内增殖繁衍的特 T cell hybridization is a new technology developed in recent years. It is another successful application of the cell fusion technology in immunological research following B cell hybridization. It is well known that normal T cells are difficult to grow long term in vitro; whereas T lymphoma cells proliferate indefinitely in vitro. After the fusion of these two cells, we expect that the traits derived from the two parental cells, respectively, can be demonstrated by progeny of T-hybridomas that have both the ability of the parental normal T cells to perform immune functions and Prostate tumor cells with in vitro culture or as xenografts in animals multiply proliferation of special