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现已认识到越来越多真核生物基因的表达是通过mRNA的稳定性调节的。最为有趣的例子是微管蛋白mRNAs不稳定性是自我调节的,一种新的机制使其不稳定,该机制涉及到微管蛋白mRNA自身成熟翻译产物(微管蛋白亚基)与刚刚从核糖体上合成的新生微管蛋白多肽的共翻译结合。
It is now recognized that the expression of more and more eukaryotic genes is regulated by the stability of the mRNA. The most interesting example is that the instability of the mRNAs of tubulin is self-regulated, a mechanism that makes them unstable, which involves the translation of the tubulin mRNA mature translocation (tubulin subunit) Co-translational Binding of Newly-synthesized Tubulin Peptides in Vivo.