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本文报道了1987年9月21-24日在巴黎召开的第一届国际抗人类红细胞及其抗原单克隆抗体会议的主要内容。用多克隆抗血清测定红细胞是鉴定血型的经典方法。最近的讨论会表明,尽管单克隆抗体(mAb)应用于常规的血型鉴定显示出良好的前景,但尚不成熟。可是,已经证明mAb在鉴定细胞抗原方面是十分有用的。长期以来,人们传统地把输血与血液学相连,其实这对输血实践并不十分有利。输血几乎完全是根据抗原-抗体反应。血液是一个器官,输血是能保证移植物和存活的唯一的例子,因此准确地说它是属于免疫学范畴。血型鉴定的起源输血和免疫学起源于同一个时期。1875年,Landois观察到一种动物血清能凝集另一种动物的
This paper reports the main contents of the first international meeting of anti-human monoclonal antibodies against human erythrocytes and their antigens held on September 21-24, 1987 in Paris. Using polyclonal antiserum to determine erythrocytes is a classic method of identifying blood types. Recent discussions have shown that although monoclonal antibodies (mAbs) have shown promising prospects for routine blood typing, they are not yet premature. However, mAbs have proven to be very useful in the identification of cellular antigens. For a long time, people have traditionally linked blood transfusions to hematology. In fact, it is not very beneficial for blood transfusion practice. Blood transfusions are almost entirely based on antigen-antibody responses. Blood is an organ and blood transfusions are the only examples that can guarantee graft and survival, so it is accurate to say that it belongs to the immunology category. The origin of blood type identification Blood transfusion and immunology originated in the same period. In 1875, Landois observed that one kind of animal serum could agglutinate another animal