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本文对67例小儿恶性淋巴瘤进行临床病理分析,其中男49例,女18例,发病年龄1.5至14岁,年龄高峰12～14岁。非何杰金氏淋巴瘤(MHL)40例,何杰金氏病(HD)27例。NHL 中以弥漫型原淋巴细胞性及无裂细胞性较多;HD 中以混合细胞型多见。小儿恶淋好发部位以结内型多于结外型,结内型以颈部最多,NHL 结外型以腹腔多见,本组 HD 无结外型。小儿恶淋预后差,31例获随访,28例死亡,病死率90.3％,其中21例在1年半内死亡。本文对小儿恶淋的特点及预后差的原因进行了讨论。
In this paper, 67 cases of pediatric malignant lymphoma were analyzed clinically and pathologically, including 49 males and 18 females, with a onset age of 1.5 to 14 years and a peak age of 12 to 14 years. 40 cases of non-Hodgkin’s lymphoma (MHL) and 27 cases of Hodgkin’s disease (HD). In NHL, diffuse pro-lymphocytic and non-cytoplasmic cells were more abundant; mixed cell types were more common in HD. Malignant lesions in children with knot more than knot shape, nodular to the neck up, NHL extranodal appearance of the more common in this group of HD without knot appearance. The poor prognosis of children with malignant lymphoma, 31 patients were followed up, 28 patients died, the fatality rate was 90.3%, of which 21 patients died within 1 year and a half. This article discusses the characteristics of children with evil and poor prognosis of the reasons are discussed.