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本文观察海拔2260米高原老年原发性高血压患者血中肾素活性、血管紧张素Ⅱ和醛固酮浓度及其相互关系。结果表明:(1)高原老年高血压患者肾素——血管紧张素——醛固酮系统处于低功能状态,(2)血管紧张素Ⅱ与醛固酮关系失调;(3)肾素分型对高原老年高血压临床意义不明。简要讨论其变化机理。
This article observes the plasma renin activity, angiotensin II and aldosterone concentrations and their relationship in senile essential hypertension patients at 2260 m altitude. The results showed that: (1) renin-angiotensin-aldosterone system in elderly patients with hypertension in the plateau is in a low-functioning state, (2) the relationship between angiotensin II and aldosterone is abnormal, and (3) Clinical significance of blood pressure is unknown. Briefly discuss its changing mechanism.