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最新研究表明,由细菌或病毒感染所导致的慢性、非可控性炎症反应与某些肿瘤有着密切的联系,它们不仅可以促进肿瘤发生,甚至会“协助”癌细胞转移至其他组织[1-3]。过去的30年里,细菌或病毒感染是癌症发生的重要危险因素这一观点已逐渐为研究者所接受[4]。世界卫生组织估计由感染性炎症所致癌症死亡比例在发展中国家占22%,发达国家占6%[5-7]。以胃癌为例,该领域研究者普遍认为胃癌的始发原因之一是胃幽门螺旋杆菌
Recent research shows that the chronic and uncontrollable inflammatory reaction caused by bacterial or viral infection is closely related to some tumors, which can not only promote the tumorigenesis but also “assist” the metastasis of cancer cells to other tissues [ 1-3]. The idea that bacterial or viral infections have been an important risk factor for cancer over the past 30 years has gradually become accepted by researchers [4]. The World Health Organization estimates that the proportion of cancer deaths caused by infectious inflammation accounts for 22% of developing countries and 6% of developed countries [5-7]. Taking gastric cancer as an example, researchers in this field generally believe that one of the causes of gastric cancer is caused by gastric Helicobacter pylori