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乙型肝炎病毒（ＨＢＶ）复制周期是Ｓｕｍｍｅｒｓ和Ｍａｓｏｎ在１９８２年观察鸭乙肝病毒（ＨＢＶ）复制后描述的〔１〕。ＨＢＶ的复制首先是ＨＢＶＤＮＡ由不完整环状的补成完整的环状ＤＮＡ，再形成超螺旋ＤＮＡ（Ｓｕｐｅｎ－ｃｏｉｌｅｄＳｃＤＮＡ），又称共价闭合...
The HBV replication cycle is described by Summers and Mason 1982 in Duck Hepatitis B virus (HBV) replication [1]. HBV replication is the first complete HBVDNA loop incomplete complement of circular DNA, and then the formation of supercoiled DNA (Supen-coiledScDNA), also known as covalent closure ...