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目的探讨CysC在CKD患者早期诊断中的临床应用。方法选择2013~2014年我科CKD患者100例作为研究组，100例体检健康者作为对照组。所有受试者取晨血，测定CysC、Scr和BUN，根据MORD公式计算eGFR，并与对照组进行比较比较。统计研究组CysC、Scr和BUN三项指标的阳性率。结果与对照组相比，研究组CysC从CKD1期开始，Scr从CKD2期起，BUN从CKD3期起有统计学意义(<0.05)；在研究组三项指标阳性统计率中CysC阳性率明显高于Scr和BUN。结论 CysC在慢性肾脏病早期检测中比Scr和BUN更有价值，是反应肾脏疾病的敏感指标。“,”Objective To explore clinical diagnostic value of Cystatin C for early chronic kidney disease. Methods In study group, we choose 100 CKD patients from 2013 to 2014 in our department, while 100 cases of healthy persons as control group. Al the subjects were morning blood, measurement of CysC、Scr and BUN, calculation of eGFR according to MORD formula, al the datas were compared with control group. To gather statistics with the positive rate of CysC、Scr and BUN. Results There were statistical significance about CysC from CKD1, Scr from CKD2, BUN from CKD3 in study group which compared with control group. The positive rate of CysC was obviously higher than Scr and BUN. Conclusion CysC has more value in clinical diagnostic for early chronic kidney disease than Scr and BUN, it is a sensitive index for kidney disease.