巯甲丙脯酸(captopril)为一种口服血管紧张素转化酶抑制剂,临床上用于重症、顽固性高血压、肾性高血压和难治性心力衰竭,取得良好的效果。过去认为其副作用发生率低、可扩大临床使用。但近年文献报告,本品亦已引起多种副作用,有的可能致命,现综述以供临床参考。 Captopril, an oral angiotensin-converting enzyme inhibitor, is clinically used in severe, refractory hypertension, renal hypertension and refractory heart failure and achieves good results. In the past that its low incidence of side effects, can expand clinical use. However, in recent years, the literature reports that this product has also caused a variety of side effects, some of which may be fatal, are reviewed for clinical reference.