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体外受精-胚胎移植(IVF-ET)技术,用于女性不孕已有20多年的历史,现代化的辅助生殖技术,使生育力有所提高,但移植成功率无明显增加。为证实丹那唑对IVF-ET反复失败妇女妊娠率的影响。作者选择1993年6月～1996年5月间,美国Keio大学医院妇产科IVF-ET研究室行IVF-ET失败的妇女82例,随机分为两组。治疗组41例,于IVF-ET失败后下一次月经第2d开始服丹那唑400mg,每日1次,共服12周,停药后第1次自然排卵3个月内行下一次IVF-ET,其中1例因全身严重皮疹而停药;对照组41例,于
In vitro fertilization-embryo transfer (IVF-ET) technology has been used for female infertility for more than 20 years. Modern assisted reproductive technology has improved fertility but no significant increase in success rate of transplantation. To confirm the effect of Danazol on the pregnancy rate of women with IVF-ET failure. Authors selected 82 patients who failed the IVF-ET IVF-ET laboratory at the Department of Obstetrics and Gynecology, Keio University Hospital, from June 1993 to May 1996, and were randomly divided into two groups. In the treatment group, 41 cases were treated with isoflurane 400 mg once daily for 2 weeks after the failure of IVF-ET on the second day of menstruation for a total of 12 weeks. The first IVF-ET was performed within 3 months after the first natural ovulation. One case of severe systemic rash and withdrawal; control group of 41 cases, at