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本文对收治的21例先天性心脏病合并肺动脉高压的患儿应用前列腺素E_1(PGE_1)治疗,经临床观察,效果满意,报告如下.临床资料一、对象:本组患儿21例,男14例,女7例,年龄11个月~6岁,体重6.5~15.0 kg.室间隔缺损18例,动脉导管未闭3例,均经多普勒超声及心脏远达片检查提示肺动脉高压.其中16例经心导管检查测得肺动脉压力,肺动脉收缩压(PP)/降主动脉收缩压(PS)大于0.7的重度肺高压5例.19例测心阻抗其射血前期/射血期(PEP/VET)均延长.
In this paper, 21 cases of congenital heart disease with pulmonary hypertension in children with prostaglandin E_1 (PGE_1) treatment, the clinical observation, the results are satisfactory, the report is as follows.Objectives: The group of 21 children, male 14 Cases, 7 females, aged 11 months to 6 years old, weighing 6.5 to 15.0 kg. Ventricular septal defect in 18 cases, patent ductus arteriosus in 3 cases, both by Doppler echocardiography and teleconnection revealed pulmonary hypertension. Pulmonary artery pressure, pulmonary artery systolic pressure (PP) / descending aorta systolic blood pressure (PS) were measured in 16 cases of severe pulmonary hypertension in 5 cases, and the mean arterial blood pressure (PEP) / VET) are extended.