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消化性溃疡几乎都在组织学上查出并发胃炎,特别是在胃窦。这种胃炎和溃疡病一般都与幽门螺杆菌(HP)感染有关,但也有人报道服阿司匹林引起的溃疡病近一半无组织学胃炎存在。因此本文作者提出非甾体类抗炎药(NSAID)相关性胃溃疡是否另有不同于 HP—胃炎—溃疡这种一般途径的发病机理存在。材料和方法选用经上消化道内窥镜诊断的未经治疗的新发胃溃疡患者,按有无服NSAID_s 史分为两组:①有服阿司匹林或其它NSMD_s 史,时间1个月以上;②无服阿司匹林或其它 NSAID_s 内窥镜下于溃疡灶边缘和距溃
Almost all peptic ulcers are histologically detected with gastritis, especially in the antrum. This gastritis and ulcer diseases are generally associated with Helicobacter pylori (HP) infection, but it was also reported nearly half of aspirin-induced ulcer disease, the presence of gastritis. Therefore, the authors propose whether NSAID-related gastric ulcer may have another pathological mechanism that is different from the general pathway of HP-gastritis-ulcer. Materials and Methods Patients with untreated gastric ulcer who had been diagnosed by upper gastrointestinal endoscopy were divided into two groups according to the history of NSAID_s: (1) taking aspirin or other NSMD_s history for more than 1 month; (2) no Serve aspirin or other NSAID_s endoscopic ulcers in the edge and ulceration