【摘 要】
：
Diabetic nephropathy caused by intensive renal cell depletion and extracellular matrix deposition is a leading cause of end-stage renal diseases in Taiwain.
【机 构】
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Division of Nephrology and Department of Medical Research Development Chang-Gung Memorial Hospital T
论文部分内容阅读
Diabetic nephropathy caused by intensive renal cell depletion and extracellular matrix deposition is a leading cause of end-stage renal diseases in Taiwain.Canonical Wnt/β-catenin signaling molecules have been reported to modulate renal tissue morphogenesis and function.However, the biological role of Wnt/β-catenin signaling pathway in high glucose-stressed glomerular mesangial cells is not well defined.We further hypothesized that Wnt signaling might be involved in regulating the fate of high glucose-stressed mesangial cells.
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