论文部分内容阅读
Objective To observe the effects of the electric acupuncture on the expression of neurocan and ethological grade during the different time of the cerebral ischemia and reperfusion in Stroke-prone-Renovascular-Hypertensive-Rats(RHRSP).Methods Stroke-prone-Renovascular-Hypertensive-Rats(RHRSP)models were established by bilaterally narrowing the renal artery with sliver loop clips and the models of rat middle cerebral artery occlusion(MCAO)were created by stringing middle cerebral artery occlusion in RHRSP.2-hour ischemia later,the effects of the electric acupuncture on the expression of neurocan and ethological grade in the rat cerebral tissue were detected by immunohistochemistry,Zea Longa 5 grade etc.after 1-day,7-day,14-day and 30-day reperfusion,which would be compared with the control group.Results The neurocan positive cells were found in the ischemic area after 2-hour ischemia and 1-day reperfusion.They increased significantly after 7-day reperfusion and up to the maximum after 14-day reperfusion.But they decreased after 30-day reperfusion.The number of neurocan positive cell in electric acupuncture group were decreased significantly after 7-day,14-day and 30-day reperfusion.The ethological grade in electric acupuncture group were markedly less than that in control group after 1-day,7-day and 30-day reperfusion.Conclusions The electric acupuncture can promote the neurofunctional recovery in cerebral ischemic area.The mechanism may be related with the regulation to the expression of neurocan.