Functional analysis of ALS-and PD-associated mutations in the signal peptide of angiogenin

来源 :华东六省一市生物化学与分子生物学学会2014年学术交流大会暨浙江省第十一届学会会员代表大会 | 被引量 : 0次 | 上传用户：yangyilong

【摘要】

：

　　Gene defects have been recognized as a prominent factor in the etiology and pathogenesis of neurodegenerative diseases, including amyotrophic lateral sclero

【作者】

：

Siqi Li Jinghao Sheng Zhengping Xu

【机构】

：

ResearchCenterofMolecularMedicine,ZhejiangUniversitySchoolofMedicine,Hangzhou,310058,China

【出处】

：

华东六省一市生物化学与分子生物学学会2014年学术交流大会暨浙江省第十一届学会会员代表大会

【发表日期】

：

2014年10期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Gene defects have been recognized as a prominent factor in the etiology and pathogenesis of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS;sporadic and familial) and Parkinsons disease (PD).

其他文献

Complete Alteration of Substrate Specificity of Two Yeast Isocitrate Dehydrogenases by Single-Point

　　Isocitrate dehydrogenase (IDH), as an old housekeeping gene and a popular star, drawing more and more attention of cancer experts. Mutation in catalytic Arg

会议

isocitrate dehydrogenasearginine mutationtumorigenesissite-directed mutagenes

Effect of Selenium-enrichedStreptomyces wh63 fermentation liquid on the growth of vegetable (Brassic

　　The effect of selenium (Se)-enriched Streptomyces wh63 fermentation liquid was investigated, which was cultured in Gause (No. 1)medium containing selenium,

会议

Streptomyces wh63selenium(Se)growth indexesbio-fertilizer

Characterization of a novel highly thermostable esterase from Gram-positivesoil bacterium Streptomyc

　　Esterase is one of the most important biocatalysts and widely used in modem industries. A novel esterase gene (estW) was cloned from Streptomyces lividans T

会议

esterasecharacterizationsubstrate specificityStreptomyces lividanshypertherm

Single-Point Mutations (R153H or R153C) in NADP+-Dependent Isocitrate Dehydrogenases from Escherichi

　　Arginine 132 (R132) mutations to histidine or cysteine frequently occur to cytosolic NADP+-isocitrate dehydrogenase (IDH1) in glioblastoma multiforme (GBM)

会议

Escherichia coliisocitrate dehydrogenasearginine mutationsite-directed mutage

生物钟基因Cry1蛋白在不同肿瘤组织中表达的研究

会议

生物钟基因Cry1肿瘤免疫组织化学

MicroRNA-409-3p suppresses colorectal cancer invasion and metastasis through GAB1 inhibition

　　Colorectal cancer (CRC) is one of the most common cancers worldwide and its metastasis accounts for the majority of the deaths. However, the molecular mecha

会议

Analysis of the expression and function of Small Heat Shock Protein 22.6 in Bombyx mori

　　Small heat shock protein (sHSP) is a family of proteins induced by heat stress. We obtained a sequence from the cDNA library constructed by our laboratory,

会议

Bombyx morisHSP22.6polyclonal antibodyheat shockmolecular chaperone

Photoreactivation of Escherichia coliImpaired at High Growth Temperatures

　　Photolyase repairs UV-induced lesions in DNA using light energy which is the principle for photoreactivation. Active photolyase contains the two-electron-re

会议

photoreactivationphotolyaseUVgrowth temperaturedifferential scanning calorim

Purification and identification of the activity of natural hemolin

　　Tostudy the function of the hemolin protein ,we analysised the Sequences of hemolin, and found the homology of Bombyx mori(domestic silkworm) with those of

会议

hemolinpurificationhigh fusion expression levelin vitroantibacterial

Gene cloning and protein functional research of TBC1D15 from Chiloscyllium Plagiosum

　　Active peptide from shark liver, APSL is a kind of Hepatic Stimulator Substance,which is separated and purified from the liver of Chiloscyllium Plagiosum an

会议

APSLTBC1D15 proteinRab-GAP activityRab7

Functional analysis of ALS-and PD-associated mutations in the signal peptide of angiogenin

其他学术论文