【摘 要】
：
Multiple MRI parameters have been used for the diagnosis and treatment of breast cancer (morphology, DCE curves,T2-weighted images, longest diameter of lesi
【机 构】
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Department of Radiology University of Minnesota Medical School USA
【出 处】
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(BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C
论文部分内容阅读
Multiple MRI parameters have been used for the diagnosis and treatment of breast cancer (morphology, DCE curves,T2-weighted images, longest diameter of lesion, and volume of lesion and spectroscopy).MRI/MRS has been used as both a diagnostic and prediction biomarker specifically using choline in vivo as a biomarker to response of chemotherapy.In vivo proton magnetic resonance spectroscopy (1H MRS) is rapidly becoming useful as a clinical tool for diagnosis and characterizing breast cancers.Alterations of the level of choline-containing metabolites are associated with malignancy.High-field MR scanners at 1.5T, 3T, 4T, and 7T have been used to evaluate the role of 1H MRS measurements of total choline containing compounds in patients with breast cancer.Newer developments in high field MR scanning and quantitative MRS may help breast imagers improve sensitivity and specificity in diagnosing and treating breast cancer.A review of results from a large MRI/MRS breast cancer study will be discussed as well as a new study ACRIN 8622 NIH 2010.This is a multi-institutional trial using spectroscopy as a biomarker for treatment response.
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