腰椎间盘的超微结构研究

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本实验通过透射电镜对大鼠、家兔及人(胎儿及成人)腰椎间盘的观察,发现纤维环由纤维软骨组成。在640 A周期性的胶原原纤维之间,可见位于隐窝内的典型软骨细胞。这些细胞常随所在部位而异。靠近周边部位的细胞更接近成纤维细胞,细胞狭长,细胞膜的扇蛤样外形渐不明显,以至消失。靠内侧的细胞类似脊索细胞,细胞核固缩,细胞质内有浓集的糖原及脂滴。纤维环呈现细胞过渡的特点。纤维环内可见弹力纤维。髓核由包含细的原纤维、颗粒及特殊结构的疏松基质所组成。在各标本中,基质内均有脊索细胞出现。细胞可单独或成堆存在,细胞质内有众多的空泡,浓集的糖原颗粒及微丝。 In this experiment, the observation of the lumbar intervertebral disc in rats, rabbits and human (fetus and adult) by transmission electron microscope revealed that the annulus fibrosus is composed of fibrocartilage. Between the 640 A periodic collagen fibrils, typical chondrocytes are located within the crypt. These cells often vary with the site. Near the peripheral parts of the cells closer to the fibroblasts, cells elongated, cell membrane fan-like appearance gradually less obvious, or even disappear. Relying on the inside of the cells similar to the cord cells, nuclear condensation, the cytoplasm of concentrated glycogen and lipid droplets. Fibrous rings show the characteristics of cell transition. Fiber ring visible elastic fibers. The nucleus consists of a loose matrix of fine fibrils, particles, and special structures. In each specimen, there were both spinal cord cells in the stroma. Cells can exist alone or in piles, the cytoplasm has a large number of vacuoles, concentrated glycogen particles and microfilaments.
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