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目的：探索兰索拉唑１５ｍｇ／ｄ和３０ｍｇ／ｄ治疗消化性溃疡的比较。方法：６３例经胃镜证实为活动性消化性溃疡病人，随机分成１５ｍｇ／ｄ组３３例，３０ｍｇ／ｄ组３０例，疗程均为４ｗｋ。疗程结束后３ｄ内复查胃镜。结果：用药４ｗｋ胃镜下溃疡愈合率（疤痕期或溃疡消失）１５ｍｇ／ｄ组为８５％，３０ｍｇ／ｄ组为８７％。２组总有效率各为１００％（Ｐ＞０．０５）。服药后中上腹疼痛消失及反酸症状消失，１５ｍｇ／ｄ组与３０ｍｇ／ｄ组依次为５．９±ｓ１．８ｄ，４．５±１．８ｄ与３．２±１．４ｄ，３．０±１．０ｄ。２组差别均有非常显著意义（Ｐ＜０．０１）。结论：口服兰索拉唑１５ｍｇ／ｄ总有效率与口服３０ｍｇ／ｄ相仿，但疼痛和反酸症状消失３０ｍｇ／ｄ组比１５ｍｇ／ｄ组更快
Objective: To explore the comparison of lansoprazole 15mg / d and 30mg / d in the treatment of peptic ulcer. Methods: Sixty-three patients with active peptic ulcer confirmed by gastroscopy were randomly divided into three groups: 15 mg / d group and 30 mg / d group, all of which were treated for 4 weeks. Gastroscopy was reviewed within 3 days after the end of treatment. Results: The ulcer healing rate (scarring or ulcer disappearance) in 4wk endoscopy was 85% in 15mg / d group and 87% in 30mg / d group. The total effective rate of two groups was 100% (P> 0.05). After taking the medicine, the pain of middle and upper abdomen disappeared and the symptom of acid reflux disappeared. The group of 15mg / d and 30mg / d were 5.9 ± s 1.8d, 4.5 ± 1.8d and 3.2 ± 1.4d, 3 respectively. 0 ± 1.0d. There were significant differences between the two groups (P <0.01). Conclusion: The total effective rate of oral lansoprazole 15mg / d is similar to that of oral 30mg / d, but the symptoms of pain and acid reflux disappear 30mg / d group is faster than 15mg / d group