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帕金森氏病(PD)是一种常见的神经退行性疾病,是常见于中老年人群的第二大神经变性疾病,它的4大临床主症表现为静止性震颤、强直、运动迟缓和姿势反射障碍。在五十岁之前很少见,而在五十岁之后该病的发病率成对数形式上升,其典型的病理特征:患者中脑黑质的多巴胺神经元大量死亡,酪氨酸羟化酶活性降低,纹状体多巴胺含量明显减少。在过去的几十年中,人们提出了遗传学、脑外伤、感
Parkinson’s disease (PD) is a common neurodegenerative disease and is the second most common neurodegenerative disease in the middle-aged and elderly population. Its four major clinical manifestations are resting tremor, ankylosis, bradykinesia, and postural Reflex obstacles. It is very rare before the age of 50, and the incidence of this disease rises logarithmically after the age of 50 with the typical pathological features of a large number of dopamine neurons in the substantia nigra of the patient, tyrosine hydroxylase Activity decreased striatum dopamine significantly reduced. In the past few decades, people have proposed genetics, brain trauma, flu