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我们于1980年1～4月使用酚妥拉明抢救9例暴发型流行性脑脊髓膜炎(简称暴脑),其中混合型3例,休克型6例,结果存活8例,死亡1例。小结如下: 9例中,男性4例,女性5例。年龄1个月～28岁(其中儿童7例)。8例患者血脑膜炎双球菌多醣体抗原测定(反向血凝法)结果7例阳性,1例阴性。1例尸检确诊。休克分型标准按全国小儿感染性休克座谈会纪要。本组休克型6例中4例重度,2例轻度休克;混合型3例中2例重度,1例轻度休克。9例患者在治疗前均有心功能不全及尿少、血非蛋白氮升高等肾功能不全表现。4例合并肺水肿。4例合并DIC。2例合并中毒性肠麻痹。
We used phentolamine from January to April 1980 to rescue 9 outbreaks of epidemic cerebrospinal meningitis (3 cases), including 3 cases of mixed type and 6 cases of shock type. The results showed that 8 cases survived and 1 died. The summary is as follows: 9 cases, 4 males and 5 females. Aged from 1 month to 28 years old (including 7 children). Eight patients with meningococcal polysaccharide antigen test (reverse hemagglutination) results in 7 cases were positive, 1 negative. 1 case of autopsy confirmed. Shock typing criteria according to the national pediatric septic shock forum summary. This group of shock type 6 cases, 4 cases of severe, 2 cases of mild shock; 3 cases of mixed type in 2 cases of severe, 1 case of mild shock. Nine patients had cardiac dysfunction and oliguria before treatment, and elevated non-protein nitrogen and other renal insufficiency. 4 cases with pulmonary edema. 4 cases combined DIC. 2 cases of toxic intestinal paralysis.