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目的 观察涤痰活血中药治疗动脉粥样硬化性椎 -基底动脉缺血 (ASVBI)的临床疗效 ,探讨其机理。方法 将80例患者随机分成西药治疗组 (低分子右旋糖酐 +西比灵 )和中药治疗组 (川芎嗪 +半夏天麻白术汤加减 ) ,检测治疗前后经颅多普勒 (TCD)及单氨氧化酶 (MDA)、超氧化物歧化酶 (SOD) ,并观察临床症状的改善。结果 中药治疗组与西药治疗组相比 ,近期临床症状改善相当 ,但中药组痊愈率明显高于西药组 (P<0 .0 5 ) ,TCD及 MDA、SOD变化的差异有显著性。结论 涤痰活血中药有清除自由基的作用 ,能有效地改善患者生活质量及脑部缺血、缺氧症状
Objective To observe the clinical efficacy of traditional Chinese medicine for treating phlegm and blood circulation in treating atherosclerotic vertebrobasilar ischemia (ASVBI) and to explore its mechanism. Methods Eighty patients were randomly divided into western medicine group (low molecular weight dextran + xibiben) and traditional Chinese medicine group (treated with ligustrazine + Banxia Mianbaizhu Decoction). Transcranial Doppler (TCD) and monoammine (MDA), superoxide dismutase (SOD), and observe the improvement of clinical symptoms. Results Compared with the western medicine group, the clinical symptoms improved significantly in the traditional Chinese medicine treatment group, but the cure rate in the traditional Chinese medicine group was significantly higher than that in the western medicine group (P <0.05). The differences in TCD, MDA and SOD were significant. Conclusion Ditan Huoxue Chinese medicine has the role of scavenging free radicals, can effectively improve the quality of life of patients and cerebral ischemia, hypoxia symptoms