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在2家医院急诊重症监护室2003年5月—2010年5月收治的395例急性中毒有机磷农药中毒患者中,按设定的入选、出院以及诊断评分标准,选取符合条件的64例为血液灌流组,常规治疗病例66例为对照组;将患者入院48 h内的时间分为入院即刻、入院16~32 h、入院40~56 h三个时相,分段记录两组患者的SOFA评分,并对各时段两组患者SOFA评分的变化进行统计学分析。结果显示,两组患者在入院即刻各系统评分无统计学意义,呼吸系统及神经系统评分灌流组第二时相、第三时相降低均优于对照组,血液系统评分对照组降低优于灌流组,循环系统及肝脏、肾脏系统评分改变两组间无统计学意义。
Among the 395 cases of acute poisoning organophosphate pesticide poisoning patients admitted to the emergency and intensive care unit of two hospitals from May 2003 to May 2010, 64 eligible patients were selected according to the criteria of selection, discharge and diagnosis. The patients in the perfusion group and the routine treatment group were treated as control group. The patients within 48 hours after admission were divided into three phases: immediate admission, 16 ~ 32 h admission, 40 ~ 56 h admission, and SOFA scores of two groups , And the changes of SOFA score of two groups of patients in each time period were statistically analyzed. The results showed that there was no significant difference between the two groups in the score of each system immediately after admission, the decrease in the second phase and the third phase in the respiratory system and nervous system score perfusion group was better than that in the control group, and the blood system score control group was better than perfusion Group, circulatory system and liver, kidney system score changes between the two groups was not statistically significant.