制取珍珠末,中国药典及中药炮制规范,都是采用传统的水飞法。鉴于原工艺生产效率低,生产周期长,且损耗率大。为此提出仍以水飞法为基本原理,采用现代粉碎工具,制备珍珠末工艺如下: 取经豆腐炮制过的珍珠,置球磨机中,加磨球及少许水,密闭,滚磨2～3hr后,加五倍水搅匀。溶液呈乳白色,倾出乳浊液,用200目筛过滤。筛内留下的粗品再置球磨机中,按上法反复打磨。合并打磨过筛之乳浊液,进行减压抽滤, The preparation of pearls, the Chinese Pharmacopoeia and the Chinese medicine concoction standards, are all based on traditional waterflies. In view of the low production efficiency of the original process, the production cycle is long and the loss rate is large. To this end, the basic principle of waterflooding is proposed, and modern pearling tools are used to prepare the pearl-end technology as follows: Take pearls made by tofu, set it in a ball mill, add grinding balls and a little water, seal and barrel for 2 to 3 hours. Add five times more water and stir well. The solution was milky white and the emulsion was decanted and filtered through a 200 mesh screen. The crude product left in the sieve is placed in a ball mill and repeatedly ground according to the above method. The screened emulsion was combined and subjected to reduced pressure filtration.