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敌杀死(溴氰菊酯Decis)是目前广泛使用的拟除虫菊酯类农药中的一种。该药入体后其作用主要是对神经的电生理效应,膜结构的损伤和离子通道的障碍,尚可使脊髓神经膜去极化期延长,出现重复动作电位,故兴奋脊髓中间神经原和周围神经。对皮肤、粘膜有刺激作用,对胆碱酯酶无直接抑制作用。我院自1985~1989年收治急性中毒19例,均为口服,其中一次服50ml左右的11例,100ml左右的4例,有4例口服量不详。治愈18例,死亡1例。
Kill (Decis) is one of the most widely used pyrethroid pesticides today. After the drug into the body its role is mainly on the electrophysiological effects of the nerves, membrane damage and ion channel barriers, can still prolong the denervation of the spinal nerve membrane, the emergence of repeated action potential, so excitement of the spinal cord and Peripheral nerves. On the skin, mucous membranes have a stimulating effect, no direct inhibition of cholinesterase. 19 cases of acute poisoning were admitted to our hospital from 1985 to 1989. All of them were taken orally. Among them, 11 cases were treated with 50ml at one time, 4 cases were at 100ml, and the oral dose was unknown in 4 cases. 18 cases were cured and 1 died.