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在我国发现30％～40％HBsAg阴性,所谓隐原性肝硬化,非甲-戊型慢性肝炎病患者仍为慢性HBV感染;有2％～3％的健康人群及献血员为低水平的HBV感染者,如供血仍可引起输血后肝炎。这是流行病学和临床工作的新课题之一。本研究在分子流行病学调查的基础上提出可能这类HBV感染与HBV变异有关。
Found in our country 30% to 40% of HBsAg-negative, so-called cryptogenic cirrhosis, non-A-type chronic hepatitis patients are still chronic HBV infection; 2% to 3% of healthy people and blood donors for low-level HBV Infected people, such as blood supply can still cause post-transfusion hepatitis. This is one of the new topics in epidemiology and clinical work. In this study, based on the molecular epidemiological survey on the possibility of such HBV infection and HBV mutation.