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目的评估本院门诊药房头孢菌素类抗生素的使用情况。方法抽取门诊处方25232张,收集含头孢菌素类药物处方2394张,进行科室、年龄分布、药物利用指数、用药天数、抗微生物药物联合用药等的统计分析。结果一代、二代、三代头孢菌素类抗生素使用频率分别为58.1%、13.2%、28.7%;病人年龄分布广泛(6d￣88岁);人均使用头孢菌素类药物天数为(4.73±3.79)d;头孢菌素类药物与其他抗微生物药物人均联合使用数为(1.38±0.57)种;部分头孢菌素类药物利用指数偏低。结论我院头孢菌素类抗生素用于婴幼儿较普遍;有相当大的比例与抗病毒药联合使用,欠合理;部分头孢菌素类药物的用量不足,应引起重视。
Objective To evaluate the use of cephalosporin antibiotics in outpatient pharmacies in our hospital. Methods Totally 25232 outpatient prescriptions were collected, 2394 prescriptions containing cephalosporins were collected, and the statistical analysis was conducted on the departments, age distribution, drug utilization index, days of drug use and combination of antimicrobial drugs. Results The frequency of use of cephalosporins was 58.1%, 13.2% and 28.7% respectively for the first generation, second generation and third generation cephalosporins. The patients were widely distributed over the age range of 6 to 88 years. The number of cephalosporins per day was 4.73 ± 3.79, d; the average number of cephalosporins used in combination with other antimicrobial agents was (1.38 ± 0.57) per cent; some cephalosporins used in medicine were low. Conclusions Our hospital cephalosporins antibiotics for infants and young children are more common; a considerable proportion of the combined use of antiviral drugs, not justified; some lack of cephalosporin drugs should be taken seriously.