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①目的了解头颈癌病人红细胞免疫功能和血清可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）水平的变化及其相互关系。②方法采用红细胞花环试验和双抗体夹心ＥＬＩＳＡ法，检测了３０例头颈癌病人红细胞Ｃ３ｂ受体花环率（Ｅ－Ｃ３ｂＲＲ）和ｓＩＬ－２Ｒ水平的变化，并与正常对照组进行比较。③结果头颈癌病人Ｅ－Ｃ３ｂＲＲ明显低于对照组，ｓＩＬ－２Ｒ水平明显高于对照组，差异均具有极显著意义（ｔ＝５．７８，３．４５，Ｐ均＜０．０１）。二者之间呈显著负相关性（ｒ＝－０．５８，Ｐ＜０．０１）。④结论Ｅ－Ｃ３ｂＲＲ和血清ｓＩＬ－２Ｒ水平的检测对头颈癌病人具有重要的临床意义
Objective To investigate the changes of erythrocyte immune function and serum soluble interleukin 2 receptor (sIL-2R) levels in head and neck cancer patients and their relationship. Methods The red blood cell rosette assay and double antibody sandwich ELISA method were used to detect the changes of erythrocyte C3b receptor rosette rate (E-C3bRR) and sIL-2R levels in 30 patients with head and neck cancer, and compared with the normal control group. 3 Results E-C3bRR in head and neck cancer patients was significantly lower than that in the control group, and the level of sIL-2R was significantly higher than that in the control group. The differences were extremely significant (t=5.78, 3.45, P<0.01). There was a significant negative correlation between the two (r=-0.58, P<0.01). 4 Conclusion E-C3bRR and serum sIL-2R levels have important clinical significance for head and neck cancer patients