A microfluidic system was developed for the synthesis of trigonal selenium(t-Se) nanowires,which was composed of a glass microchip coupled with a poly(methyl methacrylate)(PMMA) microchip.In the glass microchip, amorphous selenium(a-Se) colloid was prepared by reducing selenious acid with an excess amount of hydrazine at a temperature of 100℃.In the coupled PMMA microchip,a-Se was transformed into more stable t-Se seeds via sonication at room temperature.The residence time of the reactants in both microchips was optimized by varying the dimension and length of the microchannel each.The t-Se nanowires were formed by anisotropic growth of selenium crystallite during sonication and aging under the assistance ofβ-cyclodextrin(β-CD).Various stages of the nanowires’ growth were investigated.The as-synthesized products were characterized by powder X-Ray diffraction(XRD),Raman spectroscopy,scanning electron microscopy(SEM),transmission electron microscopy(TEM) and selected-area electron diffraction(SAED). A microfluidic system was developed for the synthesis of trigonal selenium (t-Se) nanowires, which was composed of a glass microchip coupled with a poly (methyl methacrylate) (PMMA) microchip. In the glass microchip, amorphous selenium Colloid was prepared by reducing selenious acid with an excess amount of hydrazine at a temperature of 100 ° C. In the coupled PMMA microchip, a-Se was transformed into more stable t-Se seeds via sonication at room temperature. The residence time of the reactants in both microchips was optimized by varying the dimension and length of the microchannel each. The t-Se nanowires were formed by anisotropic growth of selenium crystallite during sonication and aging under the assistance of β-cyclodextrin (β-CD) .Various stages of the nanowires ’growth were investigated.The as-synthesized products were characterized by powder X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and selected- area electron di ffraction (SAED).