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目的比较肾部分切除术(PN)和肾癌根治术(RN)对T1期肾癌的治疗效果。方法筛选确诊并行手术治疗的180例T1期肾癌患者的相关资料(PN治疗者68例,RN治疗者112例),包括性别,年龄,临床症状,手术时间,术中出血量,并根据随访了解其特异性生存率、无事件生存率及无转移生存率,分析比较这些资料来评估PN和RN在治疗T1期肾癌中的疗效。结果两组患者平均年龄、性别构成比例及临床症状相比较差异不明显,无统计学意义(>0.05)。两组患者手术时间相比较有显著差异,有统计学意义(0.05)。两组患者的5年特异性生存率、5年无事件生存率及5年无转移生存率相比较差异均不明显,均无统计学意义(>0.05)。结论尽管PN组患者平均手术时间长于RN组,但其他指标均无差异,而且PN组患者能够保留部分肾单位的功能,在生理代谢方面影响小于RN组,故在治疗T1期肾癌的疗效中二者差异不明显。对于肾功能较差的患者,选择PN优于选择RN。“,”Objective To compare the curative ef ect of treatment for T1 renal cancer by partial nephrectomy with that by radical nephrectomy.Methods The related information of 180 cases of patients with stage T1 renal cancer made a definite diagnosis and obtained surgical treatment (PN for 68 cases,RN for 112 cases)was filtrated,including gender,age,clinical symptoms,operation time and intraoperative blood loss.And specific survival,event free survival and non-metastatic survival were known according to the fol ow-up.Curative ef ect of the treatment for stage T1 renal cancer by PN and RN was evaluated through analyzing and comparing these data.Results Comparisions of average age,component percentage of gender and clinical symptoms between two groups were not evidently dif erent,and not statistical y significant ( >0.05).Operation time between two groups was a significant dif erent,and statistical y significant ( 0.05).5 years specific survival,5 years event free survival and 5 years non-metastatic survival between two groups were not obvious dif erence.And They were al no statistical significance ( >0.05).Conclusion Although the average operation time of PN group was longer than RN group,other indicators were no dif erence.Patients of PN group could be kept part of the nephron function.And physiological and metabolic ef ect in PN group was smal er than that in RN group.So the dif erence on therapeutic ef ect of treatment for T1 renal cancer was not obvious between them. For patients with poor kidney function,partial nephrectomy was superior to radical nephrectomy.