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目的:观察西红康方对糖尿病肾病(III期)患者尿白蛋白排泄率(UAER)、同型半胱氨酸(Hcy)、胱抑素C(Cys C)的影响。方法:将60例2型糖尿病患者按随机数字表法分为治疗组(30例)和对照组(32例),治疗3个月后进行总有效率、同型半胱氨酸(Hcy)、胱抑素C(Cys C)、尿微量白蛋白排泄率(UAER)的评估。结果:治疗组与对照组的总有效率比较差异有统计学意义。在改善Hcy、Cys C、UAER水平方面,治疗组均优于对照组。结论:西红康方具有改善早期糖尿病肾病患者肾功能、延缓肾功能减退的作用。
Objective: To observe the effect of Xi Hong Kang Fang on urinary albumin excretion rate (UAER), homocysteine (Hcy) and cystatin C (Cys C) in patients with diabetic nephropathy (stage III). Methods: Sixty patients with type 2 diabetes were divided into treatment group (n = 30) and control group (n = 32) by random number table. After 3 months of treatment, the total effective rate, homocysteine (Hcy) Cys C, urinary microalbumin excretion rate (UAER) assessment. Results: There was significant difference in the total effective rate between the treatment group and the control group. The improvement of Hcy, Cys C, UAER levels, the treatment group were better than the control group. Conclusion: Xi Hong Kang Fang can improve renal function in patients with early diabetic nephropathy and delay the role of renal dysfunction.