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应用PCR方法,对20例新疆Kaposi肉瘤病理组织进行了EBV和HHV-8双重感染的调查。结果:20例Kaposi肉瘤病理组织中14例检出HHV-8DNA(70%),EBV均为阴性。正常皮肤对照:10例这两种疱疹类病毒均为阴性。作者认为新疆Kaposi肉瘤的发生与EBV的相关性很小,但明显与HHV-8感染有关,但是否HHV-8感染就是新疆Kaposi肉瘤发生的决定因素,仍需进一步研究。
Using PCR, 20 cases of Xinjiang Kaposi’s sarcoma pathological tissue were investigated for EBV and HHV-8 dual infection. RESULTS: HHV-8 DNA (70%) was detected in 14 of the 20 Kaposi’s sarcoma tissues. EBV was negative. Normal skin controls: 10 cases of both herpes virus were negative. The authors believe that the incidence of Kaposi’s sarcoma in Xinjiang has little correlation with EBV, but it is obviously related to HHV-8 infection. However, whether HHV-8 infection is the determinant factor of Kaposi’s sarcoma in Xinjiang still needs further study.