已认为早孕期恶心呕吐(NVP)是十分常见的现象并为早孕诊断依据之一。虽NVP已引起人们关注,但文献很少涉及其发生机理。 NVP定义:文献命名常混淆。NVP为早孕期发生单纯恶心或恶心呕吐。有时呕吐严重,持续并干扰液体摄入及营养者称妊娠剧吐。呕吐机制及控制:“呕吐中枢”位于橄榄核水平的延髓网状结构内。在Postrema区(后穿质,延髓后部)成其附近的髓质中亦存在化学感受器细胞。该部位对水溶性物质的渗透性增加,功能上可认为在血脑屏障外。当化学感受器带受到血循环中某些化学制剂如吗啡、毛花甙C的刺激时即发生呕 Nausea and vomiting (NVP) in early pregnancy has been considered as a very common phenomenon and one of the bases for the diagnosis of early pregnancy. Although NVP has aroused people’s attention, but the literature rarely involved in its mechanism. Definition of NVP: Document naming is often confused. NVP is a simple nausea or nausea and vomiting in early pregnancy. Sometimes vomiting is serious, continuous and interfere with fluid intake and nutrition, said hyperemesis gravidarum. Vomiting mechanism and control: “vomit center” in the olivary nuclear level of the medulla oblongata structure. Chemotherapeutic cells are also present in the medulla near the Postrema area (posterior to the posterior portion of the medulla oblongata). The site of water-soluble substances increased permeability, functionally can be considered outside the blood-brain barrier. Vomiting occurs when the chemoreceptor is stimulated by certain chemicals in the bloodstream, such as morphine and cedilanid C