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目的:描述和比较上海市二级医院和三级医院中治疗急性白血病的效果。方法:用Cox回归模型对1984~1994年间上海市2535例住院治疗的急性白血病病人,按收治住院的级别不同,比较首次住院治疗的完全缓解率。结果:二级医院和三级医院急性白血病首次住院治疗的缓解率分别为52%和64%(χ2=31.0,P<0.001)。Cox回归模型分析结果显示急性白血病初治完全缓解率在三级医院是二级医院的1.3倍(95%可信限为1.13~1.47,P<0.05)。结论:不同级别医院治疗急性白血病缓解率有所不同的结果,其原因有待进一步深入研究。
Objective: To describe and compare the efficacy of treatment of acute leukemia in Shanghai’s secondary hospitals and tertiary hospitals. METHODS: The Cox regression model was used to compare the grade of hospital admissions among 2535 hospitalized patients with acute leukemia between 1984 and 1994. The complete remission rate was compared for the first hospitalization. Results: The remission rates of first hospitalization for acute leukemia in secondary and tertiary hospitals were 52% and 64%, respectively (χ2=31.0, P<0.001). Cox regression model analysis showed that the initial complete remission rate of acute leukemia was 1.3 times higher than that of the secondary hospital in the tertiary hospital (95% confidence limit was 1.13 to 1.47, P<0.05). Conclusion: Different hospitals have different results in the treatment of acute leukemia. The reasons for this need to be further studied.