论文部分内容阅读
流行性腮腺炎并发脑膜炎、脑膜脑炎118例,随机分为干扰素、病毒唑治疗组62例,男50例,女12例,年龄5岁～13岁。病毒唑对照组56例,男36例,女20例,年龄4岁～14岁。治疗方法:两组均用病毒唑10～15mg/kg·d,连用7～14天,治疗组加用人白细胞干扰素针100万单位肌注,1次/日,持续5～7天。结果发热消退时间,治疗组5.98±2.47天,对照组7.11±2.51天(P<0.05);症状开始改善时间治疗组7.95±1.67天,对照组10.11±1.94天(P<0.01);腮腺消肿时间,治疗组10.50±2.07天,对照组12.32±2.25天(P<0.01);脑电地形图好转时间治疗组2.18±0.91周,对照组2.73±0.94周(P<0.01)。
Mumps complicated with meningitis and meningoencephalitis in 118 cases were randomly divided into interferon and ribavirin treatment group of 62 cases, 50 males and 12 females, aged 5 to 13 years. Ribavirin control group 56 cases, 36 males and 20 females, aged 4 to 14 years old. Treatment: two groups were treated with ribavirin 10 ~ 15mg / kg · d, once every 7 to 14 days, the treatment group plus human leukocyte interferon needle 1 million units intramuscular injection, 1 time / day for 5 to 7 days. Results The fever subsided time was 5.98 ± 2.47 days in the treatment group and 7.11 ± 2.51 days in the control group (P <0.05). The symptom onset time was 7.95 ± 1.67 days in the treatment group and 10.11 ± 1.94 days in the control group (P <0.01) The time of the treatment group was 10.50 ± 2.07 days, and the control group was 12.32 ± 2.25 days (P <0.01). The EEG time was 2.18 ± 0.91 weeks in the treatment group and 2.73 ± 0.94 weeks in the control group (P <0.01).