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本文分别测定31例原发性肾病综合征和20例急性肾小球肾炎在不同病期尿中丙氨酸氨基肽酶(AAP)、N-乙酰-β-D-氨基葡萄糖苷酶(NAG)的排泌值,显示尿 AAP 和 NAG 测定均值在两病的极期和好转期均显著高于正常组。在缓解期,急性肾小球肾炎组恢复正常,而肾病综合征组中属肾炎型者仍略高于正常组。随病情好转,尿 AAP 和 NAG 测定均值明显下降,各病期间差异显著。结果表明,尿AAP 和 NAG 排泌值与肾小球病病情变化相一致,直接反映了肾实质受损的程度,可作为指导治疗、估计疗效和判断预后的指标。
In this paper, 31 cases of primary nephrotic syndrome and 20 cases of acute glomerulonephritis were detected in different stages of alanine aminopeptidase (AAP), N-acetyl-β-D-glucosaminidase (NAG) The excretion value of urine showed that the mean value of urinary AAP and NAG was significantly higher than that of the normal group in the extreme period and the improvement period of both diseases. In the remission period, acute glomerulonephritis group returned to normal, while nephrotic syndrome group is nephritis type is still slightly higher than the normal group. With the improvement of the condition, urinary AAP and NAG were significantly decreased mean, significantly different during each disease. The results showed that excretion of urinary AAP and NAG consistent with the changes of glomerular disease, directly reflects the extent of renal parenchyma damage can be used as a guide treatment, to assess the efficacy and prognosis of indicators.