从收集的４００余例胎儿中，任取３～９个月余胎儿１２０例，按月龄分为８个胎龄组，分别取左、右冠状动脉组织，常规制片观察。结果表明：①在第８和第９个月胎龄组中，分别有２例和４例冠状动脉壁上发现成片的泡沫细胞；②在这两组中冠状动脉壁上还发现孤立性散在平滑肌细胞增生灶，其中３例与泡沫细胞并存；③在第９个月胎龄组发现冠状动脉粥样硬化早期病变、纤维斑块各１例。纤维斑块已使管腔狭窄２５％左右。以上发现为胎儿的动脉粥样硬化早期变化提供了病理形态学依据。它在更新观念，防治动脉粥样硬化的研究，探索其病理组织发生等方面均有重要意义。 From the collection of more than 400 cases of fetuses, taking 3 to 9 months more than 120 cases of fetuses, divided into 8 groups according to age of gestational age group, respectively, left and right coronary artery tissue, routine filming observations. The results showed that: ① in the 8th and 9th month gestational age group, there were 2 and 4 cases of foam cells found on the wall of the coronary artery; ② In these two groups also found in the coronary artery wall solitary scattered Smooth muscle cell hyperplasia, of which 3 cases and foam cells co-exist; ③ In the 9th month gestational age group found early coronary atherosclerosis lesions, 1 case of fibrous plaque. Fiber plaque has lumen stenosis about 25%. The above findings provide a pathological basis for the early changes of atherosclerosis in the fetus. It is of great significance in updating concepts, preventing and treating atherosclerosis and exploring its pathological organization.