妊娠期肝内胆汁淤积症(ICP)是妊娠期特有的并发症,临床上以皮肤瘙痒、肝内胆汁淤积的血液学指标异常为特征,其主要病理学改变是胆汁淤积于肝内,但肝脏结构保持完整,肝细胞未发生炎性改变或间质细胞增生。细胞因子能调节细胞活化、分化和增殖,诱导细胞发挥功能和产生高活性分 Intrahepatic cholestasis of pregnancy (ICP) is a peculiar complication of pregnancy, the clinical pruritus, intrahepatic cholestasis hematological abnormalities characterized by the main pathological changes of cholestasis in the liver, but the liver The structure remains intact, no inflammatory changes in hepatocytes or interstitial cell proliferation occur. Cytokines can regulate cell activation, differentiation and proliferation, induce cells to function and produce high activity