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43例糖尿病性胃轻瘫患者随机分为红霉素组22例(男性13例,女性9例;年龄37±s8a)和甲氧氯普胺组21例(男性14例,女性7例;年龄35±7a),分别给予红霉素250mg和甲氧氯普胺10mg,tid,po(每餐前0.5h)。4wk为一个疗程。结果:小剂量红霉素在改善消化道症状和促进胃排空方面较甲氧氯普胺有明显效果(P<0.05)。无任何不良反应。
Forty-three patients with diabetic gastroparesis were randomly divided into two groups: 22 patients (13 males, 9 females; age 37 ± s8a) and metoclopramide group (14 males and 7 females; age 35 ± 7a) were given erythromycin 250mg and metoclopramide 10mg, tid, po (0.5h before each meal). 4wk for a course of treatment. Results: Erythromycin was effective in treating gastrointestinal symptoms and promoting gastric emptying compared with metoclopramide (P <0.05). No adverse reactions.