1973年至1990年,对陕西省黄陵县店头病区克山病消长与人体硒水平进行了动态观察。观察期间,急性(含急型和亚急型)、慢型和潜在型克山病发病率逐年下降,潜在型病情恶化率亦呈下降趋势;病区人群头发硒含量逐年上升,病情与发硒含量呈显著负相关。病区人群头发硒含量提高至非病区农村水平后,慢型和潜在型仍有新发病。 From 1973 to 1990, the dynamic changes of Keshan disease and selenium level in Shentou disease area of ​​Huangling County in Shaanxi Province were observed. During the observation period, the incidence of acute (including acute and subacute type), slow type and latent type Keshan disease decreased year by year, and the potential disease exacerbation rate also showed a downward trend; the hair selenium content in the ward increased year by year, Content was significantly negative correlation. Ward hair selenium content increased to non-ward rural areas, the slow and potential there is still a new type of disease.